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Dkk4 , a key antagonist of the Wnt/β-catenin signaling pathway, plays a precise regulatory role in hair follicle development and regeneration ( Lgr6 , a Wnt pathway co-receptor predominantly expressed in HFSCs, enhances Wnt/β-catenin signaling to support hair follicle development and regeneration ( Smad6 , an inhibitor of the BMP signaling pathway, plays a critical role in epithelial stem cell maintenance and progenitor cell differentiation ( Dvl1 , Dvl2 , and Dvl3 were highly expressed

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Conflict of Interest None declared